Chapter 14: Recovery from Injury
Functional plasticity
Several mechanisms can be distinguished when discussing a change in synaptic weights. Many of these mechanisms are included in neural network simulators such as NEURON, GENESIS, NEST, BRIAN, or VERTEX.
Structural plasticity
Simulations for recovery after peripheral lesions are described in [1].
Functional compensation
The approach of predicting which remaining brain region(s) could compensate for the loss of other brain regions is shown in [2].
References
[1] Butz, M., and A. van Ooyen. 2013. A simple rule for dendritic spine and axonal bouton formation can account for cortical reorganization after focal retinal lesions. PLOS Comput Biol 9 (10): e1003259
[2] Kaiser, Marcus. 2020. Functional compensation after lesions: Predicting site and extent of recovery. arXiv:2005.03093